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Krios Rx Cryo-TEM

Krios Rx Cryo-TEM

Cryo-TEM solution for single particle analysis dedicated to pharmaceutical research.




The Thermo Scientific Krios Rx Cryo-TEM is the flagship of the iSPA Workflow, the first pharma-dedicated solution for single particle analysis (SPA) and structure-based drug design. This high-end microscope is optimized for the drug discovery process with a guaranteed throughput of over 400 high-quality images per hour. The Krios Rx Cryo-TEM is configured for SPA only with a fixed voltage (300 kV), and comes standard equipped with a Falcon 4 Direct Electron Detector, EPU Quality Monitor, and EPU Data Management (powered by Athena Software). The simplified workflow with next-level EPU automations, including unattended multigrid data collection, makes it ideal for use by non-expert microscopists. The pharma-dedicated service package ensures the industry leading productivity and reliability with a 90% system uptime guarantee (with a Falcon 4 detector).

Key features

Industry leading productivity

Guaranteed throughput of over 400 high-quality images per hour with a Falcon 4 detector—ideal to help you generate new and repeat structures quickly to match your timeline for lead discovery and optimization

Guaranteed reliability

Accelerate Rx and Advance Rx service packages offer comprehensive support tailored for the pharma industry, including throughput validation and remote performance monitoring, to deliver a 90% instrument uptime guarantee (with a Falcon 4 detector).

Compact design

With a height less than 3 meters and the standard included iVIS active vibration dampening system, the microscope fits in a standard room, allowing easy installation and avoiding costly room renovations.


Enhanced ease of use through automation

Setup time reduced to under 30 minutes. Run the microscope unattended—including overnight or over the weekend—to collect near-atomic resolution images from multiple samples of up to 12 grids.

Future-proof platform

The automated and programmable loading door enables compatibility with robotic sample loading in the future




For more details: https://www.thermofisher.com/tr/en/home/electron-microscopy/products/transmission-electron-microscopes/krios-rx-cryo-tem.html